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Auto-Sampling USP Apparatus 3

R3000 Pro Automated Sampling Apparatus for Drug Release Using the Reciprocating Cylinder Method meets the technical require ments in 0931 Methods for Determination of Dissolution Rate and Release of the 2020 edition of the Chinese Pharmacopoeia. The reciprocating cylinder method is capable of effectively stimulating the process in which drugs are taken orally, are absorbed and take effect after dissolution and release in the stomach and bowel. In addition, the method can continuously change medium or the pH values

Functional

High-Frequency Reciprocation

Capable of satisfying the requirements for both routine and high-frequency reciprocation.

Diversified Reciprocating Mode

When multi-point sampling is performed in a single row,reciprocating frequency can be changed at different time points

Imported Sliding Table with Original Packaging

High repetitions of displacement, with stable and reliable operation

Single-Vessel, Independent,Fully-Automatic Evaporation Cover

With distinct design, the cover is capable of effectively reducing the evaporation of dissolution medium and preventing cross-contamination

500mL Large-Volume Liquid Measuring Cup

Achieve replenishment of liquid at the same temperature,and satisfy the need for repeated liquid replenishment with a large volume

Optional Dual-Row 14 Positions

Two groups of samples can be tested simultaneously in an efficient and convenient manner

Optional Imaging Module

Clearly record the testing process and the operating status of the equipment

Safety Compliance

Compliant with CHP, USP, EP, and BP technical requirements.

Three levels of the management system and operation log in compliant with FDA 21 CFR Part 11 requirements to ensure the validity and reliability of electronic data.

The interface to LIMS laboratory information managementsystem for easy connection.

Multiple alarm modes, including sampling time and temperature overload alarms, are available.

Accuracy and Reliability

Andisso USP Apparatus 3 has mechanical calibration service.

The original imported slide table is used for stable and reliable operation, and the displacement repeatability can reach ±0.025mm under unloaded conditions.

The dissolution cup is equipped with an independently automatic anti-evaporation lid design, which can reduce the evaporation of the dissolution medium while effectively preventing cross-contamination.

Extensive Functions

4-60dpm reciprocation frequency meets the needs of both conventional and high-frequency reciprocation.

The rack automatically returns to the front row for further useafter a cycle.

Diversified reciprocation modes are available. When sampling multiple points in a single row, the reciprocation frequency canbe changed at different points in time.

The 500mL dissolution cup supports the multiple times of same temperature replenishment during the experiments.

An independent cleaning path.

Pre-heating function and high-power heating are available to quickly reach the set temperature.

Optional 14 positions in double rows for simultaneous testing of two groups of samples to improve experimental efficiency.

The camera module is optional to clearly record the experimental process and machine operation status.

Technical Specifications

USP Apparatus 3	Autosampler
Instrument specifications: 7 positions and 6 rows	Sampling pipeline: 7-position syringe pump sampling
Evaporation volume: less than 1% in 24 hours at 37℃ under static condition	Sample collection: 20 rows x 12 positions
Temperature control range: room temperature to 50℃	Test tube / liquid phase vials: 240 positions
Dissolution vessel volume: 300mL	Sampling range: 0.5mL ~ 20mL
Temperature control accuracy: ±0.2℃	Maximum sampling times: 20 times
Movement of reciprocating frame: 1 ~ 10cm	Continuous working time: 3333 hours
Reciprocation frequency: 4 ~ 60dpm	Working noise: ≤50dB

LawsList

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